Open-domain ChatBot

Is it possible to build a open-domain chatbot through Rasa?

what do you mean by open domain?

i mean genric Bot. i have many technical documents or social media data and now i want train on that data

if you can formulate this data in terms of intents/entities custom actions and/or question answers then yes

Suppose i have thousands of questions and answers in Excel then how can i train.

you need to convert them into rasa response data format and use response selector: Retrieval Actions